Rapid and cost-efficient synthesis of genetic circuits.

Efficient DNA editing in mitochondria.

Non-immunogenic macromolecules and vesicles to deliver therapeutic DNA, RNA, and proteins to cells and tissues.

Increase the payload size for DNA delivery vectors by at least ten-fold.

Produce optimal epigenetic imprinting patterns in induced pluripotent stem cells (iPSC) and artificially-differentiated cells.

Generate models to predict efficiency of DNA/RNA delivery based on the structure of the payload and features of the target cell or tissue.

Rapid and cost efficient synthesis of genetic circuits.

Circuits that enable temporal control of gene therapy localization and activation.

Prevent immune system from reacting to or eliminating gene therapy.

Develop predictive models to determine optimal maintenance/scheduling of gene therapies.

Automation to rapidly design, build, and test circuit designs in mammalian cells.