Engineering Biology Objectives & Technical Achievements
Scale-up hard-to-produce therapeutic molecules, proteins, and cell therapies.
Parallel, scalable, and cost-effective genome engineering to enable the use of allogeneic cell sources, as opposed to patient-specific sources.
Engineer temperature-stable, active macromolecule- and cell-based therapies.
Design molecular features to support inexpensive, robust purification and processing of therapeutics.
Develop circuits that behave robustly across different growth media.
Develop and characterize select microbes for advanced-therapeutics production in stationary phase.
Create publicly-accessible and encrypted databases of health-related data.
Identify critical metabolic/molecular bottlenecks and work-arounds for hard-to-produce therapeutics.